HIV缩写词

1. human immunodeficiency virus type 1 (HIV-1).

2. Simian immunodeficiency virus(SIV).

3. several broadly neutralizing monoclonal antibodies(MAbs).

4. viral envelope protein (Env).

5. neutralizing antibodies (NAbs).

6. resurfaced stabilized core 3 (RSC3).

7. Envelope glycoprotein GP120 (or gp120).

8. Variable regions 1 and 2 (V1/V2).

9. HIV Envelope Proteins - glycoprotein 41, glycoprotein 120, & glycoprotein 160.

10. full-length single-chain gp120-CD4 complex (FLSC).

11. gp120 CN54, CM and Bal strains.

12. China subtype HIV-1 B′, B/C, AE/BC.

13. 2G12 and immunoglobulin G1b12 (IgG1b12 [b12]), recognize gp120, the surface subunit of Env. 2G12 targets specific carbohydrate epitopes on the heavily glycosylated silent face of gp120, while b12 targets the CD4 binding site (CD4bs). Other broadly neutralizing MAbs, 2F5, Z13, and 4E10, target the membraneproximalexternal region of gp41.

14. HIV-1 isolate JR-FL.

15. Rabbits were first inoculated with a DNA vaccine expressing the JR-FL gp120 antigen, followed by a boost with the homologous recombinant gp120, produced in CHO cells.

16. HIV-1 Env antigens from clade A, B, C, D, and E isolates.

      subtype A (92UG037.8), B(92US715.6 and Bal), C (96ZM651), and E (93TH976.17) HIV-1 isolates.

17. MAbs IgG1b12, b6, and X5, MAbs 39F, 7B2, LE311, and 15e, 2G12.

18. Pseudotypings of env genes from 92RW020, 92TH021, 92UG046, 93IN905, 94UG103, 94UG114, 98CN006, CMU02, JR-CSF,MN, NL4-3, PVO.4, QH0692.42, SC422661.8, AC10.0.29, and SF162.

19. HIV-1 env genes from SF162, SC422661.8, and SS1196 and the pSG3 Env.

20. Sera from both groups had strong reactivity to peptides derived from the C1, C2, V3, and C5 segments of gp120.

21. variable loops V1/V2, V3, V4, and V5 from individual gp120 proteins.

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